Molecular Oncology Testing, with a turnaround time of 5 days, is now available for the detection of the following mutations:

Melanoma Panel

BRAF G466A, G466E, G466V, G469A, G469E, G469R, G469S, G469V, L597Q L597R, L597S, L597V, V600E, V600K, V600L, V600R, K601E

KIT W557G, W557R, V559A, V559D, V559G, L576P, K642E, D820Y

KRAS G12A, G12C, G12D, G12F,G12R, G12S, G12V, Q61L, Q61P, Q61R

NRAS G12C, G12R, G12S, G13C, G13R, G13S, Q61E, Q61H, Q61K, Q61L, Q61P, Q61R

Colon Panel

BRAF

D594G, D594V, G469S, G469E, G469A, G469V, G469R, G469R/S, L597Q, L597V, L597R, L597S, V600E, V600G, V600K, V600M, V600L, V600L, V600E, V600D, K601E, K601Q, K601N, K601K, K601N, K601del

KRAS

A146P, A146T, A146G, A146V, A59T, G13C, G13S, G13A, G13V/I, G13D/N, G13R, G12S, G12R, G12T, G12V, G12F, G12P, G12R, G12A, G12C, G12W, G12D, G12N, G12I, G12L, G12Y, G12E, G12E, G12D/V, Q61K, Q61E, Q61L, Q61R, Q61P, Q61H, KRAS_35R, KRAS_K117E, KRAS_K117R, KRAS_176R_A59nt2, KRAS_K117N NRAS Q61H, Q61H, Q61L, Q61L, Q61R, Q61R, Q61P, Q61K, Q61E, Q61Q/K, G12S/N, G12R/P, G12C/Y, G12D/E, G12A, G12V, G13S/N, G13R, G13C/Y, G13D, G13A, G13V, NRAS_A146TPS, NRAS_A146VG, NRAS_K117E, NRAS_K117R, NRAS_176R, NRAS_175R, NRAS_K117N

Lung Panel

EGFR

R108K, T263P, A289V, A289D, G598V, T854A, L861Q, L861R, D761N,
D761Y, R776C, R776H, E709K, E709Q/H, E709A, E709G, E709V,
E709fs*1, G719S, G719C, G719A, G719D, T790M, L858M/K/R, L858R,
K745_E749del, E746_E749del, E746_A750del, E746_T751del, E746_T751>I, E746_A750>IP, E746_T751>IP, E746_S752>I,
E746_T751>A, E746del/I744_K745insKIPVAI(5' Detection, Only),
E746_A750del, E746_T751del, E746_S752del, E746_T751>I,
E746_S752>I, E746_S752>I, E746_P753>IS, E746_T751>IP,
E746_T751>Q, E746_A750>QP, E746_T751>L, E746_P753>LS,
E746_T751>S, E746K(Fwd Detection Only), E746_T751>A,
E746_S752>A, E746_T751>V, E746_T751>VAorVP, E746_P753>VS,
E746_S752>V, E746_T751>V, E746_S752>V, E746_A750>VP,
E746_T751>VA, E746_T751>VP, E746_P753>VQ,
E746V/K745_E746insVPVAIK(5' Detection, Only), E746_S752>D,
L747_A750>P, L747_T751>Q, E746_A750>DP, L747_T751>P,
L747_S752>Q, L747_S752>QH, L747_E749del,
L747_S752del/L747_S752>Q, L747_A750>P, L747_T751>P,
L747_P753>Q, L747_T751>Q, L747_S752>QH, L747_T751>A,
L747P(5' Detection, Only), L747_K754del/L747_K754>N(5 Detection,
Only), L747_T751>S, L747_T751del, L747_P753>S,
L747S/L747_K754>ST(5' Detection, Only), A750P(Rev, Detection,
Only), T751I, T751_I759>N, T751_I759>N, T751_I759>REA,
T751_I759>S(5' Detection, Only), T751_I759del(5' Detection, Only),
S752_I759del, S752_I759del, S752P, P753Q, P753_I759del,
S752Y(Rev, Detection, Only), P753S(Rev, Detection, Only),
T751_I759>S(3' Detection, Only), I759N(Rev Detection Only),
T751_I759>S(3' Detection, Only)

BRAF

D594G, D594V, G469S, G469E, G469A, G469V, G469R, G469R/S,
L597Q, L597V, L597R, L597S, V600E, V600G, V600K, V600M, V600L,
V600L, V600E, V600D, K601E, K601Q, K601N, K601K, K601N,
K601del

KRAS

A146P, A146T, A146G, A146V, A59T, G13C, G13S, G13A, G13V/I,
G13D/N, G13R, G12S, G12R, G12T, G12V, G12F, G12P, G12R, G12A,
G12C, G12W, G12D, G12N, G12I, G12L, G12Y, G12E, G12E, G12D/V,
Q61K, Q61E, Q61L, Q61R, Q61P, Q61H, KRAS_35R, KRAS_K117E,
KRAS_K117R, KRAS_176R_A59nt2, KRAS_K117N

NRAS

Q61H, Q61H, Q61L, Q61L, Q61R, Q61R, Q61P, Q61K, Q61E, Q61Q/K,
G12S/N, G12R/P, G12C/Y, G12D/E, G12A, G12V, G13S/N, G13R,
G13C/Y, G13D, G13A, G13V, NRAS_A146TPS, NRAS_A146VG,
NRAS_K117E, NRAS_K117R, NRAS_176R, NRAS_175R,
NRAS_K117N

RET Testing is also available

RET

C634R, C634W, C634Y, E632_L633del, M918T, A664D, A883F,
C634R, D631_L633>E, D631G, D898_E901del, E632_A640>VRP,
E768D, F612_C620del, F612_C620del

Requests can be made on our general referral form where you will also
find the specimen requirements.

 

 

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Contact

IGENZ Ltd
Level 2, Quay Park Health
68–70 Beach Road
Auckland

PO Box 106542
Auckland 1143
Phone 09 3073981
Fax 09 3073983
info@igenz.co.nz