Cancer Gene Tests

Cancer is defined as an uncontrolled division of abnormal cells and the malignant growth or tumour results from this division. The word cancer is a transliteration of the Greek, karkinos. Karkinos, the Greek word for crab, was used by Hippocrates to describe tumours, as on examination the veins surrounding the tumour resembled the pincers of a crab.

We offer many cancer-specific tests, which may be diagnostic, prognostic or assist with drug-targeted therapy.

ERBB2(HER2) – FISH
ERBB2(HER2) – MassARRAY®
NGS Breast Cancer Panel – Coming soon
TOP2A – FISH

BRAF – FISH
BRAF-KIAAI1549 – FISH
EGFL3-TP73, ANGPTL1-ABL2 [1p36,1q25] – FISH
EGFR – FISH
MYCN – FISH
ZNF44-ZK1-MAN2B1, GLTSCR1-GLTSCR2-CRX [19p13;19q13] – FISH
TERC – FISH
TERT – MassARRAY®

BRAF – FISH
Colon Panel – MassARRAY®
ERBB2(HER2) – FISH
GIST Panel – MassARRAY®
HRAS/Cen11 – FISH
KRAS – FISH
MET – FISH
Pancreatobiliary Tract Malignancy Panel – [p16, 3,7 and 17] – FISH
PTEN – FISH
RET – FISH
TERC – FISH
MLH1 Methylation – MassARRAY®
MPN – MassARRAY® Panel

ABL1-BCR [t(9;22)] – FISH
ATM – FISH
BCL6 – FISH
Conventional G-banded metaphase analysis
CGH+SNP Microarray
CBFB – FISH
CCND2 – FISH
CCND3 – FISH
CDKN2A [p16] – FISH
CKS1B/CDKN2C [p18) – FISH
CSF1R-PDGRB – FISH
CUX1/EZH2/D7Z1 – FISH
D13S25, LAMP1 [del13q] – FISH
D20S108 – FISH
D5S23-D5S721 [del(5p)] – FISH
E2A – FISH
EGR1 [del(5q)] – FISH
ESR1 – FISH
ETV6 – FISH
FGFR3 – FISH
IGH – FISH
IGH-BCL2 [t(14;18)] – FISH
IGH-CCND1 [t(11;14)] – FISH
IGH-FGFR3 [t(4;14)] – FISH
IGH-MAF [t(14;16)] – FISH
IGH-MAFB [t(14;20)] – FISH
MALT1 – FISH
MECOM [EVI1, inv(3)] – FISH
MPN – MassARRAY® Panel
MYB – FISH
MYCN – FISH
Lynphoma Panel – NGS (Coming soon)
PML-RARA [t(15;17)] – FISH
RELN, TES [del(7q)] – FISH
RUNX1T1-RUNX1 [t(8;21)] – FISH
TP53 – FISH
TP63 – FISH
TRA-D – FISH
TRB – FISH
TRG – FISH

ALK – FISH
BRAF – FISH
Lung Panel – MassARRAY®
ROS1 – FISH

TERC – FISH
CDKN2A [p16] – FISH
Melanoma FISH panel – RREB1, D6Z1, MYB,CCND1
CGH Microarray (for all melanomas)
p16 – FISH
Uveal Melanoma FISH panel – VHL, D3Z1, RREB1, MYB, D8Z2, MYC
TOP2A – FISH
TP53 – FISH
Melanoma Panel MassARRAY®

BCOR – FISH
CAMTA1 – FISH
CDK4 – FISH
CDKN2A [p16] – FISH
CIC – FISH
RB1, LAMP1 – FISH
D13S25, LAMP1 [del13q] – FISH
DDIT3 – FISH
ETV6 – FISH
EWSR1 – FISH
EWSR1::ERG – FISH
SMARCB1/22q12 – FISH
FGFR3 – FISH
FLI1 – FISH
FLI1::EWSR1 – FISH
FOXO1 – FISH
FUS – FISH
GLI1 – FISH
IRF4::DUSP22 – FISH
JAZF1 – FISH
MAML2 – FISH
MDM2 – FISH
MDM4 – FISH
NCOA2 – FISH
NR4A3 – FISH
NTRK1 – FISH
NTRK2 – FISH
NTRK3 – FISH
PAX3 – FISH
PDGFB – FISH
PDGFD – FISH
PDGFRB – FISH
PDGFRB – FISH
PLAG1 – FISH
PRDM10 – FISH
PRKD1 – FISH
PRKD2 – FISH
PRKD3 – FISH
TFE3 – FISH
TFEB – FISH
TGFBR3 – FISH
USP6 – FISH
WT1 – FISH
YAP1 – FISH

Urinary and Male Genital Tumours

TFE3 – FISH
TFEB – FISH
VHL – FISH
FHIT – FISH
BAP1::CCP3 – FISH
EGFR/ERBB2 [Chr7/17] – FISH

Female Genital Tumours

BCOR – FISH
JAZF1 – FISH
PHF1 – FISH
YWHAE – FISH
POLE – Coming Soon
Gynaecological Panel MassARRAY®